Independent and additive interaction between polymorphisms of tumor necrosis factor α−308 and lymphotoxin α+252 on risk of hepatocellular carcinoma related to hepatitis B

Independent and additive interaction between polymorphisms of tumor necrosis factor α−308 and lymphotoxin α+252 on risk of hepatocellular carcinoma related to hepatitis B

This case–control study was aimed to assess the effect of genetic variants of tumor necrosis factor (TNF) α−308 and lymphotoxin (LT) α+252 on development of hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC). Their gene–gene interaction was also investigated. We enrolled 200 pairs of age...

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Bibliographic Details
Main Authors: Jung-Fa Tsai, Shinn-Chern Chen, Zu-Yau Lin, Chia-Yen Dai, Jee-Fu Huang, Min-Lung Yu, Wan-Long Chuang
Format: Article
Language:English
Published: Wiley 2017-09-01
Series:Kaohsiung Journal of Medical Sciences
Subjects:
Hepatitis B related hepatocellular carcinoma
Lymphotoxin α
Single nucleotide polymorphism
Synergy index
Tumor necrosis factor α
Online Access:http://www.sciencedirect.com/science/article/pii/S1607551X17300013

Internet

http://www.sciencedirect.com/science/article/pii/S1607551X17300013

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