Structural and functional analysis of the CspB protease required for Clostridium spore germination.

Spores are the major transmissive form of the nosocomial pathogen Clostridium difficile, a leading cause of healthcare-associated diarrhea worldwide. Successful transmission of C. difficile requires that its hardy, resistant spores germinate into vegetative cells in the gastrointestinal tract. A cri...

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Bibliographic Details
Main Authors: Chloe M Adams, Brian E Eckenroth, Emily E Putnam, Sylvie Doublié, Aimee Shen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-02-01
Series:PLoS Pathogens
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23408892/?tool=EBI