Genome-wide analyses of recombination prone regions predict role of DNA structural motif in recombination.

HapMap findings reveal surprisingly asymmetric distribution of recombinogenic regions. Short recombinogenic regions (hotspots) are interspersed between large relatively non-recombinogenic regions. This raises the interesting possibility of DNA sequence and/or other cis- elements as determinants of r...

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Bibliographic Details
Main Authors: Prithvi Mani, Vinod Kumar Yadav, Swapan Kumar Das, Shantanu Chowdhury
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2635932?pdf=render