Cooperation between apoptotic and viable metacyclics enhances the pathogenesis of Leishmaniasis.

Mimicking mammalian apoptotic cells by exposing phosphatidylserine (PS) is a strategy used by virus and parasitic protozoa to escape host protective inflammatory responses. With Leishmania amazonensis (La), apoptotic mimicry is a prerogative of the intramacrophagic amastigote form of the parasite an...

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Bibliographic Details
Main Authors: João Luiz Mendes Wanderley, Lucia Helena Pinto da Silva, Poliana Deolindo, Lynn Soong, Valéria Matos Borges, Deboraci Brito Prates, Ana Paula Almeida de Souza, Aldina Barral, José Mario de Freitas Balanco, Michelle Tanny Cunha do Nascimento, Elvira Maria Saraiva, Marcello André Barcinski
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-05-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2684641?pdf=render