Phenotypic overlap between MMP-13 and the plasminogen activation system during wound healing in mice.

BACKGROUND: Proteolytic degradation of extracellular matrix is a crucial step in the healing of incisional skin wounds. Thus, healing of skin wounds is delayed by either plasminogen-deficiency or by treatment with the broad-spectrum metalloproteinase (MP) inhibitor Galardin alone, while the two pert...

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Bibliographic Details
Main Authors: Anna Juncker-Jensen, Leif R Lund
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3033913?pdf=render