Characterization of negative feedback network motifs in the TGF-β signaling pathway.

The transforming growth factor-β (TGF-β) superfamily of cytokines plays a fundamental role in a wide variety of cellular processes, including growth, differentiation, apoptosis, and tissue homeostasis [corrected]. Its relevance is emphasized by the mutations of its core components that are associate...

Full description

Bibliographic Details
Main Authors: Daniel Nicklas, Leonor Saiz
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3875243?pdf=render