G-quadruplexes may determine the landscape of recombination in HSV-1

G-quadruplexes may determine the landscape of recombination in HSV-1

Abstract Background Several lines of evidence suggest that recombination plays a central role in replication and evolution of herpes simplex virus-1 (HSV-1). G-quadruplex (G4)-motifs have been linked to recombination events in human and microbial genomes, but their role in recombination has not been...

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Bibliographic Details
Main Authors: Nandhini Saranathan, Banhi Biswas, Anupam Patra, Perumal Vivekanandan
Format: Article
Language:English
Published: BMC 2019-05-01
Series:BMC Genomics
Subjects:
Herpes simplex virus-1
G-quadruplexes
Recombination breakpoints
Higher-order G4 s
G4- clusters
Online Access:http://link.springer.com/article/10.1186/s12864-019-5731-0

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http://link.springer.com/article/10.1186/s12864-019-5731-0

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