Anti-Metastatic Effects on Melanoma via Intravenous Administration of Anti-NF-κB siRNA Complexed with Functional Peptide-Modified Nano-Micelles

Anti-Metastatic Effects on Melanoma via Intravenous Administration of Anti-NF-κB siRNA Complexed with Functional Peptide-Modified Nano-Micelles

Controlling metastasis is an important strategy in cancer treatment. Nanotechnology and nucleic acids with novel modalities are promising regulators of cancer metastasis. We aimed to develop a small interfering RNA (siRNA) systemic delivery and anti-metastasis system using nanotechnology. We previou...

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Bibliographic Details
Main Authors: Hisako Ibaraki, Takanori Kanazawa, Minami Owada, Keiko Iwaya, Yuuki Takashima, Yasuo Seta
Format: Article
Language:English
Published: MDPI AG 2020-01-01
Series:Pharmaceutics
Subjects:
polymer nano-micelles
sirna
systemic delivery
metastasis
melanoma
nf-κb
rela
functional peptide
Online Access:https://www.mdpi.com/1999-4923/12/1/64

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https://www.mdpi.com/1999-4923/12/1/64

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