SAM domain-based protein oligomerization observed by live-cell fluorescence fluctuation spectroscopy.
Sterile-alpha-motif (SAM) domains are common protein interaction motifs observed in organisms as diverse as yeast and human. They play a role in protein homo- and hetero-interactions in processes ranging from signal transduction to RNA binding. In addition, mutations in SAM domain and SAM-mediated o...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2008-04-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC2291563?pdf=render |