Soluble CD83 Triggers Resolution of Arthritis and Sustained Inflammation Control in IDO Dependent Manner

Soluble CD83 Triggers Resolution of Arthritis and Sustained Inflammation Control in IDO Dependent Manner

Interference with autoimmune-mediated cytokine production is a key yet poorly developed approach to treat autoimmune and inflammatory diseases such as rheumatoid arthritis. Herein, we show that soluble CD83 (sCD83) enhances the resolution of autoimmune antigen-induced arthritis (AIA) by strongly red...

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Bibliographic Details
Main Authors: Dmytro Royzman, Darja Andreev, Lena Stich, Manfred Rauh, Tobias Bäuerle, Stephan Ellmann, Louis Boon, Markus Kindermann, Katrin Peckert, Aline Bozec, Georg Schett, Alexander Steinkasserer, Elisabeth Zinser
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-04-01
Series:Frontiers in Immunology
Subjects:
soluble CD83
arthritis
IDO
osteoclasts
Tregs
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.00633/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.00633/full

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