Acute Lung Injury Results from Innate Sensing of Viruses by an ER Stress Pathway

Incursions of new pathogenic viruses into humans from animal reservoirs are occurring with alarming frequency. The molecular underpinnings of immune recognition, host responses, and pathogenesis in this setting are poorly understood. We studied pandemic influenza viruses to determine the mechanism b...

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Bibliographic Details
Main Authors: Eike R. Hrincius, Swantje Liedmann, David Finkelstein, Peter Vogel, Shane Gansebom, Amali E. Samarasinghe, Dahui You, Stephania A. Cormier, Jonathan A. McCullers
Format: Article
Language:English
Published: Elsevier 2015-06-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124715005240