Cardiovascular tissue regeneration system based on multiscale scaffolds comprising double-layered hydrogels and fibers

Abstract We report a technique to reconstruct cardiovascular tissue using multiscale scaffolds incorporating polycaprolactone fibers with double-layered hydrogels comprising fibrin hydrogel surrounded by secondary alginate hydrogel. The scaffolds compartmentalized cells into the core region of cardi...

Full description

Bibliographic Details
Main Authors: Yun-Min Kook, Soonjae Hwang, Hyerim Kim, Ki-Jong Rhee, Kangwon Lee, Won-Gun Koh
Format: Article
Language:English
Published: Nature Publishing Group 2020-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-77187-8