RAINBOW: Haplotype-based genome-wide association study using a novel SNP-set method.

Difficulty in detecting rare variants is one of the problems in conventional genome-wide association studies (GWAS). The problem is closely related to the complex gene compositions comprising multiple alleles, such as haplotypes. Several single nucleotide polymorphism (SNP) set approaches have been...

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Bibliographic Details
Main Authors: Kosuke Hamazaki, Hiroyoshi Iwata
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-02-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1007663