Anesthesia-Induced Hypothermia Attenuates Early-Phase Blood-Brain Barrier Disruption but Not Infarct Volume following Cerebral Ischemia.

Blood-brain barrier (BBB) disruption is thought to facilitate the development of cerebral infarction after a stroke. In a typical stroke model (such as the one used in this study), the early phase of BBB disruption reaches a peak 6 h post-ischemia and largely recovers after 8-24 h, whereas the late...

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Bibliographic Details
Main Authors: Yu-Cheng Liu, Yu-Da Lee, Hwai-Lee Wang, Kate Hsiurong Liao, Kuen-Bao Chen, Kin-Shing Poon, Yu-Ling Pan, Ted Weita Lai
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5261567?pdf=render