Interleukin-1 beta and neurotrophin-3 synergistically promote neurite growth <it>in vitro</it>

Interleukin-1 beta and neurotrophin-3 synergistically promote neurite growth <it>in vitro</it>

<p>Abstract</p> <p>Pro-inflammatory cytokines such as interleukin-1 beta (IL-1β) are considered to exert detrimental effects during brain trauma and in neurodegenerative disorders. Consistently, it has been demonstrated that IL-1β suppresses neurotrophin-mediated neuronal cell surv...

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Bibliographic Details
Main Authors: Boato Francesco, Hechler Daniel, Rosenberger Karen, Lüdecke Doreen, Peters Eva M, Nitsch Robert, Hendrix Sven
Format: Article
Language:English
Published: BMC 2011-12-01
Series:Journal of Neuroinflammation
Subjects:
interleukin 1 beta
IL-1β
neurotrophin 3
NT-3
NGF
spinal cord
brain slices
neurite growth
axon outgrowth
neuroplasticity
Online Access:http://www.jneuroinflammation.com/content/8/1/183

Internet

http://www.jneuroinflammation.com/content/8/1/183

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