Model and Algorithm for Linkage Disequilibrium Analysis in a Non-equilibrium Population

The multilocus analysis of polymorphisms has emerged as a vital ingredient of population genetics and evolutionary biology. A fundamental assumption used for existing multilocus analysis approaches is Hardy-Weinberg equilibrium (HWE) at which maternally- and paternally-derived gametes combine random...

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Bibliographic Details
Main Authors: Jingyuan eLiu, Zhong eWang, Yaqun eWang, Runze eLi, Rongling eWu
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-07-01
Series:Frontiers in Genetics
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2012.00078/full