EAT-18 is an essential auxiliary protein interacting with the non-alpha nAChR subunit EAT-2 to form a functional receptor.

EAT-18 is an essential auxiliary protein interacting with the non-alpha nAChR subunit EAT-2 to form a functional receptor.

Nematode parasites infect approximately 1.5 billion people globally and are a significant public health concern. There is an accepted need for new, more effective anthelmintic drugs. Nicotinic acetylcholine receptors on parasite nerve and somatic muscle are targets of the cholinomimetic anthelmintic...

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Bibliographic Details
Main Authors: Shivani Choudhary, Samuel K Buxton, Sreekanth Puttachary, Saurabh Verma, Gunnar R Mair, Ciaran J McCoy, Barbara J Reaves, Adrian J Wolstenholme, Richard J Martin, Alan P Robertson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-04-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1008396

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https://doi.org/10.1371/journal.ppat.1008396

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