Evolutionary and Topological Properties of Genes and Community Structures in Human Gene Regulatory Networks.

The diverse, specialized genes present in today's lifeforms evolved from a common core of ancient, elementary genes. However, these genes did not evolve individually: gene expression is controlled by a complex network of interactions, and alterations in one gene may drive reciprocal changes in...

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Bibliographic Details
Main Authors: Anthony Szedlak, Nicholas Smith, Li Liu, Giovanni Paternostro, Carlo Piermarocchi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-06-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC4928929?pdf=render