Hapl-o-Mat: open-source software for HLA haplotype frequency estimation from ambiguous and heterogeneous data

Hapl-o-Mat: open-source software for HLA haplotype frequency estimation from ambiguous and heterogeneous data

Abstract Background Knowledge of HLA haplotypes is helpful in many settings as disease association studies, population genetics, or hematopoietic stem cell transplantation. Regarding the recruitment of unrelated hematopoietic stem cell donors, HLA haplotype frequencies of specific populations are us...

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Bibliographic Details
Main Authors: Christian Schäfer, Alexander H. Schmidt, Jürgen Sauter
Format: Article
Language:English
Published: BMC 2017-05-01
Series:BMC Bioinformatics
Subjects:
HLA
Immunogenetics
Population genetics
Bioinformatics
Haplotype
Expectation-maximization algorithm
Online Access:http://link.springer.com/article/10.1186/s12859-017-1692-y

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http://link.springer.com/article/10.1186/s12859-017-1692-y

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