CAG-encoded polyglutamine length polymorphism in the human genome

<p>Abstract</p> <p>Background</p> <p>Expansion of polyglutamine-encoding CAG trinucleotide repeats has been identified as the pathogenic mutation in nine different genes associated with neurodegenerative disorders. The majority of individuals clinically diagnosed with s...

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Main Authors: Hayden Michael R, Yuen Macaire MS, Yang George S, Wilkinson Anna, Lee Soo, Neal Scott J, Meynert Alison M, Mead Carri-Lyn, Huang Yong, Devon Rebecca S, Butland Stefanie L, Holt Robert A, Leavitt Blair R, Ouellette BF Francis
Format: Article
Language:English
Published: BMC 2007-05-01
Series:BMC Genomics
Online Access:http://www.biomedcentral.com/1471-2164/8/126