Mutation analysis of the <it>MDM4 </it>gene in German breast cancer patients

<p>Abstract</p> <p>Background</p> <p>MDM4 is a negative regulator of p53 and cooperates with MDM2 in the cellular response to DNA damage. It is unknown, however, whether <it>MDM4 </it>gene alterations play some role in the inherited component of breast cance...

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Bibliographic Details
Main Authors: Bogdanova Natalia, Jin Haiyan, Wilhelm Bettina, Govbakh Lina, Reincke Scarlett, Bremer Michael, Karstens Johann H, Dörk Thilo
Format: Article
Language:English
Published: BMC 2008-02-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/8/52