Mutation analysis of the <it>MDM4 </it>gene in German breast cancer patients
<p>Abstract</p> <p>Background</p> <p>MDM4 is a negative regulator of p53 and cooperates with MDM2 in the cellular response to DNA damage. It is unknown, however, whether <it>MDM4 </it>gene alterations play some role in the inherited component of breast cance...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2008-02-01
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Series: | BMC Cancer |
Online Access: | http://www.biomedcentral.com/1471-2407/8/52 |