The aryl hydrocarbon receptor is constitutively active in advanced prostate cancer cells.

Distant prostate cancers are commonly hormone refractory and exhibit increased growth no longer inhibited by androgen deprivation therapy. Understanding all molecular mechanisms contributing to uncontrolled growth is important to obtain effective treatment strategies for hormone refractory prostate...

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Bibliographic Details
Main Authors: Oliver Richmond, Maryam Ghotbaddini, Cidney Allen, Alice Walker, Shokouh Zahir, Joann B Powell
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3995675?pdf=render