Renal allograft rejection, lymphocyte infiltration, and de novo donor-specific antibodies in a novel model of non-adherence to immunosuppressive therapy

Renal allograft rejection, lymphocyte infiltration, and de novo donor-specific antibodies in a novel model of non-adherence to immunosuppressive therapy

Abstract Background Non-adherence has been associated with reduced graft survival. The aim of this study was to investigate the immunological mechanisms underlying chronic renal allograft rejection using a model of non-adherence to immunosuppressive therapy. We used a MHC (major histocompatibility c...

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Bibliographic Details
Main Authors: Louisa Kühne, Bettina Jung, Helen Poth, Antonia Schuster, Simone Wurm, Petra Ruemmele, Bernhard Banas, Tobias Bergler
Format: Article
Language:English
Published: BMC 2017-12-01
Series:BMC Immunology
Subjects:
Donor specific antibodies
Humoral rejection
Renal transplantation
Non-adherence
Leukocyte infiltration
BAFF
Online Access:http://link.springer.com/article/10.1186/s12865-017-0236-6

Internet

http://link.springer.com/article/10.1186/s12865-017-0236-6

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