A Herpesviral Immediate Early Protein Promotes Transcription Elongation of Viral Transcripts
Herpes simplex virus 1 (HSV-1) genes are transcribed by cellular RNA polymerase II (RNA Pol II). While four viral immediate early proteins (ICP4, ICP0, ICP27, and ICP22) function in some capacity in viral transcription, the mechanism by which ICP22 functions remains unclear. We observed that the FAC...
Main Authors: | , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
American Society for Microbiology
2017-06-01
|
Series: | mBio |
Online Access: | http://mbio.asm.org/cgi/content/full/8/3/e00745-17 |