Reversal of cocaine-conditioned place preference through methyl supplementation in mice: altering global DNA methylation in the prefrontal cortex.

Analysis of global methylation in cells has revealed correlations between overall DNA methylation status and some biological states. Recent studies suggest that epigenetic regulation through DNA methylation could be responsible for neuroadaptations induced by addictive drugs. However, there is no in...

Full description

Bibliographic Details
Main Authors: Weiping Tian, Mei Zhao, Min Li, Tianbao Song, Min Zhang, Li Quan, Shengbin Li, Zhong Sheng Sun
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3306398?pdf=render