Dexamethasone Causes Hypertension in Rats Even Under Chemical Blockade of Peripheral Sympathetic Nerves

Dexamethasone Causes Hypertension in Rats Even Under Chemical Blockade of Peripheral Sympathetic Nerves

Synthetic glucocorticoids (GCs) are widely used to treat inflammatory conditions. However, chronic use of GCs can lead to hypertension. The cause of this undesired side effect remains unclear. Previously, we developed an in vivo rat model to study the mechanisms underlying hypertension induced by th...

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Bibliographic Details
Main Authors: Alexandra E. Soto-Piña, Cynthia Franklin, C. S. Sheela Rani, Elizabeth Fernandez, Elías Cardoso-Peña, Alejandra D. Benítez-Arciniega, Helmut Gottlieb, Carmen Hinojosa-Laborde, Randy Strong
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-12-01
Series:Frontiers in Neuroscience
Subjects:
dexamethasone
hypertension
adrenal medulla
6-OHDA
renal denervation
sympathetic nerves
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2019.01305/full

Internet

https://www.frontiersin.org/article/10.3389/fnins.2019.01305/full

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