Transcriptomic biomarkers for tuberculosis: evaluation of DOCK9, EPHA4, and NPC2 mRNA expression in peripheral blood.

Transcriptomic biomarkers for tuberculosis: evaluation of DOCK9, EPHA4, and NPC2 mRNA expression in peripheral blood.

Lately, much effort has been made to find mRNA biomarkers for tuberculosis (TB) disease fection with microarray-based approaches. In a pilot investigation, through RNA sequencing technology, we observed a prominent modulation of DOCK9, EPHA4, and NPC2 mRNA abundance in the blood of TB patients. To c...

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Bibliographic Details
Main Authors: Leonardo Silva De Araujo, Lea A.I. Vaas, Marcelo Ribeiro-Alves, Robert Geffers, Fernanda Carvalho Queiroz Mello, Alexandre Silva de Almeida, Adriana da Silva Resende Moreira, Afrânio Lineu Kritski, José Roberto Lapa e Silva, Milton Ozório Moraes, Frank Pessler, Maria Helena Féres Saad
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-10-01
Series:Frontiers in Microbiology
Subjects:
Tuberculosis
messenger RNA
M. tuberculosis
LTBI
biomarkers.
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2016.01586/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fmicb.2016.01586/full

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