Activation of a neural stem cell transcriptional program in parenchymal astrocytes

Activation of a neural stem cell transcriptional program in parenchymal astrocytes

Adult neural stem cells, located in discrete brain regions, generate new neurons throughout life. These stem cells are specialized astrocytes, but astrocytes in other brain regions do not generate neurons under physiological conditions. After stroke, however, striatal astrocytes undergo neurogenesis...

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Bibliographic Details
Main Authors: Jens P Magnusson, Margherita Zamboni, Giuseppe Santopolo, Jeff E Mold, Mauricio Barrientos-Somarribas, Carlos Talavera-Lopez, Björn Andersson, Jonas Frisén
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-08-01
Series:eLife
Subjects:
neurogenesis
astrocytes
neural stem cells
single-cell RNA sequencing
regenerative medicine
Online Access:https://elifesciences.org/articles/59733

Internet

https://elifesciences.org/articles/59733

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