Design of Novel Compounds with the Potential of Dual PPARγ/α Modulation for the Management of Metabolic Syndrome

This study sought to identify a single molecule capable of managing all three manifestations of metabolic syndrome–hyperglycaemia, dyslipidaemia and hypertension. Two Protein Data Bank (PDB) depositions were selected and used to establish the baseline affinity that any designed molecule in this stud...

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Bibliographic Details
Main Authors: Claire Ellul, Claire Shoemake
Format: Article
Language:English
Published: KenzPub 2017-12-01
Series:Nuclear Receptor Research
Subjects:
Online Access:http://www.kenzpub.com/journals/nurr/2017/101311/