CSF parvalbumin levels reflect interneuron loss linked with cortical pathology in multiple sclerosis

CSF parvalbumin levels reflect interneuron loss linked with cortical pathology in multiple sclerosis

Abstract Introduction and methods In order to verify whether parvalbumin (PVALB), a protein specifically expressed by GABAergic interneurons, could be a MS‐specific marker of grey matter neurodegeneration, we performed neuropathology/molecular analysis of PVALB expression in motor cortex of 40 post‐...

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Bibliographic Details
Main Authors: Roberta Magliozzi, Marco Pitteri, Stefano Ziccardi, Anna Isabella Pisani, Luigi Montibeller, Damiano Marastoni, Stefania Rossi, Valentina Mazziotti, Maddalena Guandalini, Caterina Dapor, Gianmarco Schiavi, Agnese Tamanti, Richard Nicholas, Richard Reynolds, Massimiliano Calabrese
Format: Article
Language:English
Published: Wiley 2021-03-01
Series:Annals of Clinical and Translational Neurology
Online Access:https://doi.org/10.1002/acn3.51298

Internet

https://doi.org/10.1002/acn3.51298

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