Retinal ganglion cell loss is accompanied by antibody depositions and increased levels of microglia after immunization with retinal antigens.

<h4>Background</h4>Antibodies against retinal and optic nerve antigens are detectable in glaucoma patients. Recent studies using a model of experimental autoimmune glaucoma demonstrated that immunization with certain ocular antigens causes an immun-mediated retinal ganglion cell loss in...

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Bibliographic Details
Main Authors: Stephanie C Joachim, Oliver W Gramlich, Panagiotis Laspas, Heiko Schmid, Sabine Beck, Harald D von Pein, H Burkhard Dick, Norbert Pfeiffer, Franz H Grus
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22848388/pdf/?tool=EBI