Exosomes from MiR-30d-5p-ADSCs Reverse Acute Ischemic Stroke-Induced, Autophagy-Mediated Brain Injury by Promoting M2 Microglial/Macrophage Polarization

Exosomes from MiR-30d-5p-ADSCs Reverse Acute Ischemic Stroke-Induced, Autophagy-Mediated Brain Injury by Promoting M2 Microglial/Macrophage Polarization

Background/Aims: Recent studies have indicated that exosomes secreted from adipose-derived stem cells (ADSCs) have important effects in the treatment of ischemic injury. However, the treatment mechanism is unclear. This study aimed to investigate whether ADSC-derived exosomes enriched with microRNA...

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Bibliographic Details
Main Authors: Mei Jiang, Hairong Wang, Mingming Jin, Xuelian Yang, Haifeng Ji, Yufeng Jiang, Hanwen Zhang, Feifei Wu, Guolu Wu, Xiaoyin Lai, Liying Cai, Rongguo Hu, Limin Xu, Longxuan Li
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2018-05-01
Series:Cellular Physiology and Biochemistry
Subjects:
Acute ischemic stroke
MiR-30d-5p
Microglial/macrophage polarization
Autophagy
Exosome
Online Access:https://www.karger.com/Article/FullText/490078

Internet

https://www.karger.com/Article/FullText/490078

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