Comprehensive assessment of exposure to clozapine in association with side effects among patients with treatment-resistant schizophrenia: a population pharmacokinetic study

Background: There have been scarce data on the distribution of clozapine concentrations in comparison with the recommended range (350–600 ng/ml) or their relationship with side effects among patients with treatment-resistant schizophrenia. Furthermore, no studies have assessed the association betwee...

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Bibliographic Details
Main Authors: Nobuyuki Nomura, Kohei Kitagawa, Ryuhei So, Fuminari Misawa, Masafumi Kodama, Hiroyoshi Takeuchi, Robert Bies, Thomas Straubinger, Christopher Banker, Yuya Mizuno, Masaru Mimura, Hiroyuki Uchida
Format: Article
Language:English
Published: SAGE Publishing 2021-05-01
Series:Therapeutic Advances in Psychopharmacology
Online Access:https://doi.org/10.1177/20451253211016189