Oligomerization of ZFYVE27 (Protrudin) is necessary to promote neurite extension.

ZFYVE27 (Protrudin) was originally identified as an interacting partner of spastin, which is most frequently mutated in hereditary spastic paraplegia. ZFYVE27 is a novel member of FYVE family, which is implicated in the formation of neurite extensions by promoting directional membrane trafficking in...

Full description

Bibliographic Details
Main Authors: D V Krishna Pantakani, Marta M Czyzewska, Anna Sikorska, Chiranjeevi Bodda, Ashraf U Mannan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3247280?pdf=render