The IL23-IL17 Immune Axis in the Treatment of Ulcerative Colitis: Successes, Defeats, and Ongoing Challenges

The IL23-IL17 Immune Axis in the Treatment of Ulcerative Colitis: Successes, Defeats, and Ongoing Challenges

Ulcerative colitis (UC) is a chronic relapsing disorder of the colonic tract, characterized by a dysregulated innate and adaptive immune response to gut microbiota that contributes to the perpetuation of intestinal inflammatory processes. The Interleukin (IL) 23/IL17 axis has been reported to play a...

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Bibliographic Details
Main Authors: Daniele Noviello, Riccardo Mager, Giulia Roda, Riccardo G. Borroni, Gionata Fiorino, Stefania Vetrano
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Immunology
Subjects:
ulcerative colitis
IBD
IL23
IL17
ustekinumab
mirikizumab
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.611256/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.611256/full

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