Metabolic influences that regulate DC function in tumors

Dendritic cells (DC) are critical regulators of both activation and tolerance in the adaptive immune response. The dual nature of DC immunoregulatory function depends on their differentiation and activation status. DC found within the tumor microenvironment (TME) and tumor draining lymph node often...

Full description

Bibliographic Details
Main Authors: Timothy Nicholas James Bullock, Han eDong
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-01-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2014.00024/full