Genetic determinants of human health span and life span: progress and new opportunities.

We review three approaches to the genetic analysis of the biology and pathobiology of human aging. The first and so far the best-developed is the search for the biochemical genetic basis of varying susceptibilities to major geriatric disorders. These include a range of progeroid syndromes. Collectiv...

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Bibliographic Details
Main Authors: George M Martin, Aviv Bergman, Nir Barzilai
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-07-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC1934400?pdf=render