A Quinol Anion as Catalytic Intermediate Coupling Proton Translocation With Electron Transfer in E. coli Respiratory Complex I

A Quinol Anion as Catalytic Intermediate Coupling Proton Translocation With Electron Transfer in E. coli Respiratory Complex I

Energy-converting NADH:ubiquinone oxidoreductase, respiratory complex I, plays a major role in cellular energy metabolism. It couples NADH oxidation and quinone reduction with the translocation of protons across the membrane, thus contributing to the protonmotive force. Complex I has an overall L-sh...

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Bibliographic Details
Main Authors: Franziska Nuber, Luca Mérono, Sabrina Oppermann, Johannes Schimpf, Daniel Wohlwend, Thorsten Friedrich
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Chemistry
Subjects:
NADH dehydrogenase
respiratory complex I
bioenergetics
proton-coupled electron transfer
quinone chemistry
Escherichia coli
Online Access:https://www.frontiersin.org/articles/10.3389/fchem.2021.672969/full

Internet

https://www.frontiersin.org/articles/10.3389/fchem.2021.672969/full

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