Tight junctions in Hailey-Hailey and Darier’s diseases
Hailey-Hailey disease (HHD) and Darier’s disease (DD) are caused by mutations in Ca2+-ATPases with the end result of desmosomal disruption and suprabasal acantholysis. Tight junctions (TJ) are located in the granular cell layer in normal skin and contribute to the epidermal barrier. Aberrations in t...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
PAGEPress Publications
2009-11-01
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| Series: | Dermatology Reports |
| Subjects: | |
| Online Access: | http://www.pagepress.org/journals/index.php/dr/article/view/1353 |