Advances in HBV infection and replication systems in vitro

Abstract Background Hepatitis B virus (HBV) is a DNA virus belonging to the Hepadnaviridae family that has limited tissue and species specificity. Due to the persistence of HBV covalently closed circular DNA (cccDNA) in host cells after HBV infection, current antiviral drugs cannot eradicate HBV. Th...

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Bibliographic Details
Main Authors: Ruirui Xu, Pingping Hu, Yuwen Li, Anran Tian, Jun Li, Chuanlong Zhu
Format: Article
Language:English
Published: BMC 2021-05-01
Series:Virology Journal
Subjects:
HBV
Online Access:https://doi.org/10.1186/s12985-021-01580-6