Expression of Interleukin-8 Correlates with Angiogenesis, Tumorigenicity, and Metastasis of Human Prostate Cancer Cells Implanted Orthotopically in Nude Mice

We determined whether the expression of interleukin-8 (IL-8) by human prostate cancer cells correlates with induction of angiogenesis, tumorigenicity, and production of metastasis. Low and high IL-8-producing clones were isolated from the heterogeneous PC-3 human prostate cancer cell line. The secr...

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Bibliographic Details
Main Authors: Sun Jin Kim, Hisanori Uehara, Takashi Karashima, Marya Mccarty, Nancy Shih, Isaiah J. Fidler
Format: Article
Language:English
Published: Elsevier 2001-01-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558601800142