Obacunone reduces inflammatory signalling and tumour occurrence in mice with chronic inflammation-induced colorectal cancer

Context Obacunone, a limonoid abundantly found in Citrus fruits, exhibits a variety of bioactivities. Objective To investigate the effects of obacunone on a colorectal cancer (CRC) mouse model, and clarify its potential molecular mechanisms. Materials and methods The male Balb/c mice were induced wi...

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Bibliographic Details
Main Authors: Xiaoping Luo, Zhilun Yu, Bei Yue, Junyu Ren, Jing Zhang, Sridhar Mani, Zhengtao Wang, Wei Dou
Format: Article
Language:English
Published: Taylor & Francis Group 2020-01-01
Series:Pharmaceutical Biology
Subjects:
Online Access:http://dx.doi.org/10.1080/13880209.2020.1812673