DNA methylome signatures of prenatal exposure to synthetic glucocorticoids in hippocampus and peripheral whole blood of female guinea pigs in early life
Abstract Synthetic glucocorticoids (sGC) are administered to women at risk of preterm delivery, approximately 10% of all pregnancies. In animal models, offspring exposed to elevated glucocorticoids, either by administration of sGC or endogenous glucocorticoids as a result of maternal stress, show in...
Main Authors: | Aya Sasaki, Margaret E. Eng, Abigail H. Lee, Alisa Kostaki, Stephen G. Matthews |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2021-01-01
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Series: | Translational Psychiatry |
Online Access: | https://doi.org/10.1038/s41398-020-01186-6 |
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