Human Cytomegalovirus Infection Upregulates the Mitochondrial Transcription and Translation Machineries

Human Cytomegalovirus Infection Upregulates the Mitochondrial Transcription and Translation Machineries

Infection with human cytomegalovirus (HCMV) profoundly affects cellular metabolism. Like in tumor cells, HCMV infection increases glycolysis, and glucose carbon is shifted from the mitochondrial tricarboxylic acid cycle to the biosynthesis of fatty acids. However, unlike in many tumor cells, where a...

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Bibliographic Details
Main Authors: S. Karniely, M. P. Weekes, R. Antrobus, J. Rorbach, L. van Haute, Y. Umrania, D. L. Smith, R. J. Stanton, M. Minczuk, P. J. Lehner, J. H. Sinclair
Format: Article
Language:English
Published: American Society for Microbiology 2016-03-01
Series:mBio
Online Access:http://mbio.asm.org/cgi/content/full/7/2/e00029-16

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http://mbio.asm.org/cgi/content/full/7/2/e00029-16

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