Lipoic acid prevents acrylamide-induced neurotoxicity in CD-1 mice and BV2 microglial cells via maintaining redox homeostasis

Lipoic acid prevents acrylamide-induced neurotoxicity in CD-1 mice and BV2 microglial cells via maintaining redox homeostasis

Acrylamide (ACR) is known as a contaminant generated in starchy foods during cooking at high-temperature. In this study, pre-treatment with LA improved gait abnormalities and mnemonic and exploration ability of CD-1 male mice administrated with ACR. Alleviative effect of LA was further observed on h...

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Bibliographic Details
Main Authors: Ge Song, Zhigang Liu, Qian Liu, Xuebo Liu
Format: Article
Language:English
Published: Elsevier 2017-08-01
Series:Journal of Functional Foods
Subjects:
Acrylamide
Lipoic acid
Central nervous system
Microglial
Myeloperoxidase
Online Access:http://www.sciencedirect.com/science/article/pii/S175646461730316X

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http://www.sciencedirect.com/science/article/pii/S175646461730316X

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