Multiple nivolumab-induced CNS demyelination with spontaneous resolution in an asymptomatic metastatic melanoma patient

Multiple nivolumab-induced CNS demyelination with spontaneous resolution in an asymptomatic metastatic melanoma patient

Abstract Background Immune checkpoint inhibitors (ICPis) have revolutionised the treatment of melanoma by significantly increasing survival rates and disease control. However, ICPis can have specific immune-related adverse events, including rare but severe neurological toxicity. Case presentation We...

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Bibliographic Details
Main Authors: Vincent Pillonel, Vincent Dunet, Andreas F. Hottinger, Gregoire Berthod, Luis Schiappacasse, Solange Peters, Olivier Michielin, Veronica Aedo-Lopez
Format: Article
Language:English
Published: BMJ Publishing Group 2019-12-01
Series:Journal for ImmunoTherapy of Cancer
Subjects:
Immune checkpoint inhibitors
Nivolumab
Immune related adverse events
Neurological toxicities
CNS demyelination
Metastatic melanoma
Online Access:http://link.springer.com/article/10.1186/s40425-019-0818-3

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http://link.springer.com/article/10.1186/s40425-019-0818-3

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