Mutation detection sensitivity of high resolution melting in clinical samples: a comparative study between formamide and dimethyl sulfoxide

High-resolution melting (HRM) is one of the widely used methods for mutation detection. Sometimes, mutations which are rare but clinically important may not be detected. Thus, increasing sensitivity of HRM based mutation detection method is essential. This study was particularly aimed to establish H...

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Bibliographic Details
Main Authors: Dipa Roy, Md. Mahmudul Hasan, Ariful Haque
Format: Article
Language:English
Published: Bangladesh Society for Microbiology, Immunology, and Advanced Biotechnology 2019-08-01
Series:Journal of Advanced Biotechnology and Experimental Therapeutics
Subjects:
Online Access:http://www.ejmanager.com/fulltextpdf.php?mno=36799