Validation and Automation of a High-Throughput Multitargeted Method for Semiquantification of Endogenous Metabolites from Different Biological Matrices Using Tandem Mass Spectrometry

Validation and Automation of a High-Throughput Multitargeted Method for Semiquantification of Endogenous Metabolites from Different Biological Matrices Using Tandem Mass Spectrometry

The use of metabolomics profiling to understand the metabolism under different physiological states has increased in recent years, which created the need for robust analytical platforms. Here, we present a validated method for targeted and semiquantitative analysis of 102 polar metabolites that cove...

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Bibliographic Details
Main Authors: Jatin Nandania, Gopal Peddinti, Alberto Pessia, Meri Kokkonen, Vidya Velagapudi
Format: Article
Language:English
Published: MDPI AG 2018-08-01
Series:Metabolites
Subjects:
high-throughput
targeted
semiquantitation
metabolomics
LC-MS
multianalyte method
validation
cross-platform comparability
automation
biomarkers
Online Access:http://www.mdpi.com/2218-1989/8/3/44

Internet

http://www.mdpi.com/2218-1989/8/3/44

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