Bim and Mcl-1 exert key roles in regulating JAK2<sup>V617F </sup>cell survival

<p>Abstract</p> <p>Background</p> <p>The JAK2<sup>V617F </sup>mutation plays a major role in the pathogenesis of myeloproliferative neoplasms and is found in the vast majority of patients suffering from polycythemia vera and in roughly every second patient s...

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Bibliographic Details
Main Authors: Guthy Daniel A, Andraos Rita, Qian Zhiyan, Rubert Joëlle, Radimerski Thomas
Format: Article
Language:English
Published: BMC 2011-01-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/11/24