Genistein Enhances the Radiosensitivity of Breast Cancer Cells via G2/M Cell Cycle Arrest and Apoptosis

Genistein Enhances the Radiosensitivity of Breast Cancer Cells via G2/M Cell Cycle Arrest and Apoptosis

The aim of the present study was to investigate the radiosensitizing effect of genistein, and the corresponding mechanisms of action on breast cancer cells with different estrogen receptor (ER) status. Human breast cancer cell lines such as MCF-7 (ER-positive, harboring wild-type p53) and MDA-MB-231...

Full description

Bibliographic Details
Main Authors: Li Gong, Qiang Li, Ting Zhao, Fei Ye, Xiaodong Jin, Ping Li, Chao Sun, Xiongxiong Liu
Format: Article
Language:English
Published: MDPI AG 2013-10-01
Series:Molecules
Subjects:
breast cancer cells
radiosensitivity
genistein
G2/M arrest
apoptosis
Online Access:http://www.mdpi.com/1420-3049/18/11/13200

Internet

http://www.mdpi.com/1420-3049/18/11/13200

Similar Items